The in-hospital mortality from severe sepsis (30%) and septic shock (50%) remains extremely high. Sepsis is a complex syndrome that is difficult to define, diagnose, and treat. It is a range of clinical conditions caused by the body's systemic response to infection, and is one of the leading causes of death in hospital. Rapid and timely intervention is critical to successful treatment.
Are patients presenting with sepsis currently managed appropriately according to best practice guidelines?
Retrospective audit
Sample: 50 consecutive Emergency Department patient records
Criteria
Inclusion: Patients over 18 years old coded as Sepsis, Infection or shock (Including Hypotension and Infection.)
The internationally agreed definitions of Severe Sepsis/ Septic Shock should be used (see attached documentation).
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1st December 2008
Date | Patients | Measured | Results | Standard | Regional avg. |
---|---|---|---|---|---|
01st December 2008 | Patients with infection OR sepsis as their primary diagnosis | Management of the pateints according to the criteria | Documented evidence that blood cultures were obtained prior to antibiotics being administered in the ED | 100 % | 65 % |
Documented evidence that serum lactate measurement obtained prior to leaving the ED | 100 % | 87 % | |||
Documented evidence that first intravenous fluid bolus (up to 20mls/kg) was given in 75% of cases within 1 hour of arrival | 100 % | 58 % | |||
Documented evidence that antibiotics were administered in 90% of cases within 2 hours of arrival | 100 % | 71 % |
Improvements in most criteria, but still significant scope for improvement to achieve target. However, huge improvement in the use of goal directed therapy, which almost achieves target.
Significant scope for improvement across the board.